Individuals in mid-career positions in higher education typically feel that they are faced with fewer engagement endeavors and new initiatives with which they can participate in as institutions tend to find them not as new and their ideas no longer as cutting edge, even though they very well may be. For women in academia, this phenomenon is even more complex. Typically, by mid-career, women have survived the sprint to tenure while juggling family/caregiver responsibilities. Post-tenure they may find themselves in a space where they have more control over their work and can engage at a more comfortable pace. However, without institutional support and personal determination to remain engaged, women may find themselves facing stagnation in their career development. Thus, it is essential that mentorship opportunities are established, and career trajectories put in place, for mid-career women. This book considers specific challenges, issues, strategies, and solutions that are associated with female academics during mid-career phases. The book includes a variety of emerging evidence-based professional practice and narrative personal accounts as written by administrators, faculty, staff, and students. The book considers strategies for remaining vibrant and productive and suggestions from successful mid-career women academics and reflections from women who have passed the mid-career phase. Covering topics such as tenure, self-care, and academic leadership, this reference work is ideal for administrators, faculty, policymakers, academicians, scholars, researchers, practitioners, instructors, and students.